The World's First Catheter with Integrated Distal Tip Vibration
Deep Vein Thrombosis (DVT)
Clot formed in the deep vein, typically in the leg
Venous Thromboembolism
900k
>50%
15%
5%
Cases in the US
DVT Patients will be diagnosed with a PE
Mortality in Hospitalized PE Patients
Occurrence of PE "Lollipopping"
or "Corking"
Pulmonary Embolism (PE)
Clot migrating from the legs obstruct the pulmonary artery to the lung
First-Gen Solutions
Limitations:
Design Targets:
-
Prolonged hospital stay in ICU
-
​Introduces significant bleeding risks
-
Marginally effective
-
Slow improvement of pulmonary perfusion
-
Not applicable treatment method for high-risk patients that require urgent treatment
-
Focused on usage of thrombolytics to break up present clots
- Catheter-Directed Thrombolysis for focused and consistent infusion of thrombolytic into the clot region
-
Ultrasound-Assisted Thrombolysis for increased delivery of thrombolytics to the clot
-
Improve blood flow and prevent damage to surrounding tissues
Limitations:
Second-Gen Solutions
-
Demonstrate the clinical efficacy of aspiration thrombectomy
-
Navigate through tortuous anatomy to reach and retrieve the clot
-
Withstand suction forces without collapsing
-
Reduce rate of corking/occlusion
-
Reduce hospital stay
-
Thrombus can "cork" the catheter tip allowing for potential embolization
-
Vessels can collapse around the catheter during suction preventing clot ingestion
-
Using “stronger suction” can result in clinically significant blood loss
-
Large bore catheters impart larger forces during navigation and delivery, increasing potential for vascular injury
Design Targets:
Next-Gen: Our Solution
Vibrating
Distal Tip
No Capital Equipment
May Reduce Procedural Blood Loss
Low Profile
Improved Trackability
May Improve Clot Removal Efficiency
Pre-Clinical Testing, June 2023
Clinical Advisors
Get to Know Us
Headquartered in Buffalo, New York, Vicora is the first portfolio company of Egret Healthcare Ventures. Founded to help create a sustainable start up ecosystem that fosters medical device innovation, Egret Healthcare Ventures includes a seasoned group of partners across finance, healthcare, innovation, product development and the regulatory world. They have a strong track record of successful startup business creation, advancement and exits. Working collaboratively with regional strengths and centers of excellence, Egret Healthcare Ventures is building a disruptive portfolio of innovative companies driven by clinical and technological advancement.
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