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The World's First Catheter with Integrated Distal Tip Vibration

Clinical Need
Deep Vein Thrombosis

Deep Vein Thrombosis (DVT)

Clot formed in the deep vein, typically in the leg

Venous Thromboembolism

900k

>50%

15%

5%

Cases in the US

DVT Patients will be diagnosed with a PE

Mortality in Hospitalized PE Patients

Occurrence of PE "Lollipopping"

or "Corking"

Pulmonary Embolism

Pulmonary Embolism (PE)

Clot migrating from the legs obstruct the pulmonary artery to the lung

First-Gen Solutions

Limitations:

Design Targets:

  • Prolonged hospital stay in ICU

  • ​Introduces significant bleeding risks 

  • Marginally effective

  • Slow improvement of pulmonary perfusion

  • Not applicable treatment method for high-risk patients that require urgent treatment

  • Focused on usage of thrombolytics to break up present clots 

  • Catheter-Directed Thrombolysis for focused and consistent infusion of thrombolytic into the clot region 
  • Ultrasound-Assisted Thrombolysis for increased delivery of thrombolytics to the clot

  • Improve blood flow and prevent damage to surrounding tissues

Limitations:

Second-Gen Solutions

  • Demonstrate the clinical efficacy of aspiration thrombectomy

  • Navigate through tortuous anatomy to reach and retrieve the clot

  • Withstand suction forces without collapsing

  • Reduce rate of corking/occlusion

  • Reduce hospital stay

  • Thrombus can "cork" the catheter tip allowing for potential embolization

  • Vessels can collapse around the catheter during suction preventing clot ingestion

  • Using “stronger suction” can result in clinically significant blood loss

  • Large bore catheters impart larger forces during navigation and delivery, increasing potential for vascular injury

Design Targets:

Our Solution

Next-Gen: Our Solution

Vibrating

Distal Tip

No Capital Equipment

May Reduce Procedural Blood Loss

Low Profile

Improved Trackability

May Improve Clot Removal Efficiency

Pre-Clinical Testing, June 2023

Team

Clinical Advisors

Dr. Jan Engstrom

Dr. Jan Engström

Interventional Radiologist

Karolinska University Hospital

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Dr. Asma Kaliq

Dr. Asma Khaliq

Interventional Cardiologist​

​Montefiore Medical Center

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Dr. John Moriarty

Interventional Radiologist

David Geffen School of Medicine at UCLA 

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Dr. David Holmes

Dr. David Holmes

Interventional Cardiologist

Mayo Clinic

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Dr. Chris Manion

Dr. Chris Manion

Interventional Cardiologist 

Gates Vascular Institute 

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Dr. David Zlotnick

Dr. David Zlotnick

Interventional Cardiologist 

Gates Vascular Institute 

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Industry Partners

Strategic Partners

Resolution Medical
Jacobs Institute
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Hemologyx
Yageo Group KEMET
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Get to Know Us

Headquartered in Buffalo, New York, Vicora is the first portfolio company of Egret Healthcare Ventures. Founded to help create a sustainable start up ecosystem that fosters medical device innovation, Egret Healthcare Ventures includes a seasoned group of partners across finance, healthcare, innovation, product development and the regulatory world. They have a strong track record of successful startup business creation, advancement and exits. Working collaboratively with regional strengths and centers of excellence, Egret Healthcare Ventures is building a disruptive portfolio of innovative companies driven by clinical and technological advancement.

About Us
News

Latest News

Two Medical Device Startups Launch in Buffalo with Seed Funding

October 12, 2022 | Press Release

Two Local Medical Device Startups on the Road to Commercialization

December 8, 2023 | News Article

UB CAT Funds Ten Life Sciences Research Projects

December 11, 2023 | News Article

UB CAT Announces R&D Collaboration Awards to Eight Life Sciences Companies

September 25, 2024 | News Article

UB CAT Supports Nine Faculty-Industry Life Sciences R&D Projects

September 27, 2024 | News Article

Contact Us

CONTACT US

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701 Ellicott Street

Buffalo, NY 14203

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